3D TUMOROIDS TO REPLICATE THE PATIENT’S ORIGINAL TUMOR
At 2cureX we grow tumor replicas, called tumoroids, from cell clusters from the patient’s tumors. The three-dimensional structures better replicate the original tumor biology, including heterogeneity, than two-dimensional methods and so provide a more reliable prediction of the patient’s response to a specific treatment.
TREATMENT GUIDANCE POWERED BY ARTIFICIAL INTELLIGENCE / MACHINE LEARNING
The effect of the cancer drugs on the tumoroids is assessed by capturing and interpreting small variations in size and shape and comparing those variations with a vast proprietary database of reference images. We have developed our own Convolutional Neural Network that combines data from brightfield and fluorescence images of the tumoroids in a dynamic analysis and converts them into a quantitative measurement of response to treatment.
TAILORED FOR CLINICAL USE
2cureX offers IndiTreat® tests as a lab service. The use of the IndiTreat® technology in a clinical setting has been validated in the TICC trial, the first prospective interventional trial, in which a 3D functional test was used to guide treatment.
The design of the various drug panels supports specific treatment decisions throughout the patient lifecycle, and the cost and turnaround time make the IndiTreat® tests suitable for use in clinical practice. Turnaround time from biopsy to the final report is around three weeks.